Positron emission particle tracking in living animal

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Positron emission particle tracking (PEPT) has been used in a living subject for the first time, according to a new study from the School of Biomedical Engineering & Imaging Sciences. The study, published in the journal Nature Medicine, reports the use of PEPT to track the movement of nanoparticles in a living mouse. The researchers say that PEPT could be used to study a wide range of biological processes, including drug delivery and disease progression.

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Positron Emission Particle Tracking: A Revolutionary Breakthrough in Biomedical Imaging

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Published on: February 5, 2023 Description: A quick animation on the Positron Emission Particle Tracking (PEPT) technique, which is used for research of granular systems.

Positron Emission Particle Tracking (PEPT)

In a groundbreaking study, researchers from the School of Biomedical Engineering & Imaging Sciences have successfully employed positron emission particle tracking (PEPT) technology in a living animal subject for the first time. This groundbreaking achievement opens up new avenues for exploring the intricate dynamics of blood flow and other physiological processes in unprecedented detail.

Positron Emission Particle Tracking: Deciphering the Mysteries of Blood Flow

PEPT technology allows scientists to track the movement of a single radioactive particle within a living organism, providing valuable insights into the flow of blood and other fluids. This capability holds immense potential for studying hemodynamics, the science of blood flow, and understanding how blood moves through our vessels.

従来のPETイメージング法では、何十億もの放射性分子を患者に注入し、その平均分布を一定時間、通常10～30分かけて画像化します。これでは、これらの分子の速度や体内の正確な位置をリアルタイムで知ることができません。これは、血流の研究や血管内の血流の仕方を知るのに役立ちます。

PEPTは、単一粒子をリアルタイムで追跡することで、現在他のイメージングモダリティでは研究不可能な、血流の速度、密度、全体的なダイナミクスを研究することが可能になるはずです。全身レベルでの血行動態の研究は、臨床用の全身PETスキャナーが利用できるようになったため、特にタイムリーです。そのうちの1台は、まもなくキングスに設置される予定です。

Positron Emission Particle Tracking: Unveiling the Potential in Biomedicine

The applications of PEPT technology extend far beyond hemodynamics. It holds promise for evaluating abnormal events in cardiovascular diseases and cancer, where blood flow plays a crucial role. By analyzing blood flow and pressure gradients within lesions, such as tumors or vascular lesions, clinicians can gain valuable insights to guide treatment options for patients.

Positron Emission Particle Tracking: A Glimpse into the Future of Medical Imaging

The successful implementation of PEPT in a living animal subject marks a significant milestone in biomedical imaging. As the technology continues to advance, we can expect to witness groundbreaking applications that revolutionize the way we diagnose and treat diseases.

Wrapping Up

The advent of PEPT technology has opened up a new frontier in biomedical imaging, offering unprecedented insights into the intricate workings of our bodies. With its ability to track single particles in real time, PEPT holds immense potential for studying blood flow, evaluating disease processes, and ultimately improving patient care. As research in this field progresses, we can eagerly anticipate even more remarkable discoveries and applications of this groundbreaking technology.

FAQ’s

1. What is Positron Emission Particle Tracking (PEPT) technology?

PEPT technology allows scientists to track the movement of a single radioactive particle within a living organism, providing valuable insights into the flow of blood and other fluids.

2. How does PEPT differ from conventional PET imaging techniques?

Conventional PET imaging techniques inject billions of radioactive molecules into a patient and image their average distribution over time. PEPT, on the other hand, tracks a single particle in real time, enabling the study of blood flow velocity, density, and overall dynamics.

3. What are the potential applications of PEPT technology in biomedicine?

PEPT technology has potential applications in studying hemodynamics, evaluating abnormal events in cardiovascular diseases and cancer, and guiding treatment options for patients.

4. How does PEPT technology advance the field of biomedical imaging?

PEPT technology offers unprecedented insights into the intricate workings of our bodies by tracking single particles in real time. It revolutionizes the way we diagnose and treat diseases and opens up new avenues for groundbreaking applications.

5. What is the future of PEPT technology in medical imaging?

As research in this field progresses, we can expect to witness even more remarkable discoveries and applications of PEPT technology, leading to advancements in disease diagnosis, treatment, and patient care.

Links to additional Resources:

1. https://www.kcl.ac.uk/ 2. https://www.ncbi.nlm.nih.gov/ 3. https://www.nature.com/.